This document includes questions and answers that pertain to the ARPA-E Funding Opportunity Announcement (FOA) entitled "Design Intelligence Fostering Formidable Energy Reduction and Enabling Novel Totally Impactful Advanced Technology Enhancements (DIFFERENTIATE) (SBIR/STTR)".  The full solicitation on the DIFFERENTIATE SBIR/STTR FOA and additional information can be found on the ARPA-E Funding Opportunity Exchange website (https://arpa-e-foa.energy.gov).