Simplifying Reactor Setup for Cell-Free Biofuel Production

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Exploratory Topics
Monrovia, California
Project Term:
08/08/2022 - 08/07/2024

Technology Description:

Invizyne will develop efficient cell-free enzyme cascade reactions as an alternative, more commercially competitive approach to microbe-produced biofuels. Cell-free technology is still relatively new. However, Invizyne has already been successful in improving enzyme stability and process optimization to push down the cost curve of biofuels. The team seeks to address a barrier to market penetration for cell-free technologies by simplifying and reducing the cost of enzyme production. If successful, this approach could enable a cell-free enzyme system that produces isobutanol at below $3 per gallon gasoline equivalent.


ARPA-E Program Director:
Dr. Simon Freeman
Project Contact:
Dr. Tyler Korman
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