Simplifying Reactor Setup for Cell-Free Biofuel Production
Program:
Exploratory Topics
Exploratory Topics
Award:
$496,177
$496,177
Location:
Monrovia, California
Monrovia, California
Status:
ACTIVE
Project Term:
08/08/2022 - 08/07/2024
08/08/2022 - 08/07/2024
Technology Description:
Invizyne will develop efficient cell-free enzyme cascade reactions as an alternative, more commercially competitive approach to microbe-produced biofuels. Cell-free technology is still relatively new. However, Invizyne has already been successful in improving enzyme stability and process optimization to push down the cost curve of biofuels. The team seeks to address a barrier to market penetration for cell-free technologies by simplifying and reducing the cost of enzyme production. If successful, this approach could enable a cell-free enzyme system that produces isobutanol at below $3 per gallon gasoline equivalent.
Contact
ARPA-E Program Director:
Dr. Simon Freeman
Project Contact:
Dr. Tyler Korman
Press and General Inquiries Email:
ARPA-E-Comms@hq.doe.gov
Project Contact Email:
Tyler@invizyne.com
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• Northwestern University - LOwering CO2: Models to Optimize Train Infrastructure, Vehicles, and Energy Storage (LOCOMOTIVES)
• Northwestern University - Inter Modal Analytics for Green Infrastructure Network Energy Decarbonization (IMAGINED)
• Oak Ridge National Laboratory (ORNL) - A Portable Diagnostic Package For Spectroscopic Measurement of Key Plasma Parameters In Transformative Fusion Energy Devices
• OCOchem - High Aspect Ratio CO2 Reduction Electrolyzer via Novel Gas Diffusion Electrode - Design
• Oklahoma State University (OSU) - Establishing Validation Sites for Field-Level Emissions Quantification from Grain Sorghum in Southern Great Plains
• Oregon State University (OSU) - Development of Thermodynamic and Kinetic Simulation Tools and Testing Procedures For Enhanced Durability of Concrete Containing Industrial By-Products
• Origen Hydrogen - Engineering of Scalable Platinum-free Electrodes for Pure-Water AEM Water Electrolysis
• Osmoses - Efficient Recovery of Dilute Helium Gas Using Molecular Sieve Membranes
• Otherlab - SeaSTAR: Selective Thalassic Ambulatory Retriever
• Pacific Industrial Development Corporation - Biomimetic CO2 to Fuel Enabled by Scalable Catalyst Development and Synthetic Electrochemistry
• Pacific Northwest National Laboratory (PNNL) - Exploring Macroalgae as Critical Mineral Crops, E=(MC)2
• Pacific Northwest National Laboratory (PNNL) - UNrealized Critical Lanthanide Extraction via Sea Algae Mining (UNCLE-SAM): Domestic production of critical minerals from seawater
• Pennsylvania State University (Penn State) - Synthesis of Consists as Rolling Energy micro-grids (SCORE)
• Pennsylvania State University (Penn State) - Cryogenic Solid-state Circuit Breaker
• Perseus Materials - Variable Cross-sectional Casting: New Composite Fabrication Process for Wind Turbine Blades
• pH Matter - Type V Vessel-Aided Electrochemical Compression for Ultra-High Pressure Electrolysis
• Phoenix Tailings - Novel Technique for Domestic Rare Earth Oxide Separation and Rare Earth Metal Reduction
• Phytodetectors - Functional Engineering of a Photosynthetic Desalination Pump Circuit
• Princeton Plasma Physics Laboratory (PPPL) - A Portable Ion-Energy Diagnostic for Transformative ARPA-E Fusion Energy R&D
• Princeton University - Highly Efficient Charged Particle Beam Injection into Magnetically Confined Plasmas
• Princeton University - Electricity System Capacity Expansion and Operational Modeling for Evaluation and Optimization of Flexible Carbon Capture and Sequestration Systems
• Raytheon Technologies Research Center - Multi-Material Topology Optimization for High Performance Heat Exchangers
• RTX Technologies Research Center (RTRC) - CONFIRMMS: CONtrail Forecasting through In-situ Reliable Multisourced Modeling and Sensing
• Rutgers University - Waste-to-Energy (WTE)-Derived Low-Carbon-Footprint Concrete (LCFC)
• Sequoia Scientific - Real-time, In-situ Sensing of Sediment Properties for Environmental Monitoring of Deep-Sea Polymetallic Nodule Mining Real-time, In-situ Sensing of Sediment Properties for Environmental Monitoring of Deep-Sea Polymetallic Nodule Mining
• Siemens - Multi-Physics Topology Optimization for Dual Flow Heat Exchangers
• SiTration - Low-Cost Recycling of Lithium from Batteries via Conductive Membrane Nanofiltration
• Southern Research Institute - Machine Learning for Automated Maintenance of Future MSR
• Stanford University - Co-Synthesis of Hydrogen and High-Value Carbon Products from Methane Pyrolysis
• Stanford University - Nuclear Product Detection from Deuterated Nanoparticles under Phonon Stimulation
• Stoicheia - Discovery Platform for Low-Ir Anode Catalysts in PEM Electrolyzers
• Sublime Systems - Electrochemical Synthesis of Low-Carbon Cement
• Sylvatex - Breakthrough Process to Manufacture Very Low-cost LFP Cathode for Li-ion Batteries
• Texas Tech University - Advanced Materials Characterization and Nuclear Product Detection for LENR
• Texas Tech University - Development of Cubic Boron Nitride (c-BN) Ultrawide Bandgap Semiconductors
• The Boeing Company - Contrail INformation for Collaborative Operations (CINCO)
• The Boeing Company - Multidisciplinary Topology Optimization of Extreme Environment Heat Exchangers
• The City College of New York - Gypsum & Clay-Based Additives to MSW for Pre-Combustion Enhancement of Syngas and Solid Residue Improvement
• Tufts University - Living Filter Design for High-throughput, Low-cost Recovery of Critical Materials
• UHV Technologies - Highly Efficient Vacuum Smelting of Aluminum
• Ultra-low Loss Technologies - Space Division Multiplexing with Multi-Core Fiber for Energy Efficient Integrated Photonic Networking Technologies
• Ultrasonic Technology Solutions - Extremely Fast and Efficient Direct Contact Ultrasonic Drying for Roll To Roll Manufacturing
• Umaro Foods - Marine Bio-Ore Mining of Rare Earth Elements
• Universities Space Research Association - Physics & Machine Learning Based Aviation Contrails Prediction and Observation System
• University of Alaska Fairbanks - Assessments of Geochemistry, Concentration, and Scalability of REEs Recovery from Seaweeds
• University of California, Berkeley (UC Berkeley) - Ligand Facilitated Bioaccumulation: Biomining of Rare Earth and Other Critical Metals from Electronic Wastes
• University of California, Davis (UC Davis) - Electron Density Profile Measurements Using USPR
• University of California, Davis (UC Davis) - Carbon-Negative Buildings Assessment and Tool (CaNBAT)
• University of California, Los Angeles (UCLA) - Low-Temperature Architected Cementation Agents (LAMINAE)
• University of California, San Diego (UC San Diego) - Extremely Durable and Low-Cost Concrete: Ultralow Binder Content and Ultrahigh Tensile Ductility
• University of Colorado, Boulder (CU-Boulder) - Geopolymer Cements: Resistance-Engineered Sewer Infrastructure For Longevity Using Innovative, Energy-Efficient, Synthesis Techniques (RESILIENT)
• University of Connecticut - Detection and Fixation - A Lifecycle-management Framework Towards an SF6-Free Green Power Network
• University of Connecticut - Topology Optimization Of Additively Manufactured Heat-Exchanger Plates For Enhanced Performance (TOP-HEX)
• University of Florida - Boron Concrete For Active Formation of Lithium As Mitigation of Neutron-Induced Expansion and Passive Neutron Absorption
• University of Houston - Low-Cost, High-Rate Fabrication of High-Performance, Uniform, Long REBCO Conductors
• University of Illinois, Urbana-Champaign (UIUC) - Rapid AI-based Dissection of Ashes using Raman and XRF Spectroscopy (RADAR-X)
• University of Illinois, Urbana-Champaign (UIUC) - Midwest Bioenergy Crop Landscape Laboratory (MBC-Lab): Capturing Spatio-temporal and Managerial Variations to Provide a Gold Standard Data and Platform for Validating Field-level Emission from Bioenergy Crops
• University of Kentucky - Belite Cement, and Concretes; Novel Low-Energy Approaches To Making Concrete Extremely Durable
• University of Michigan - Electrochemical Direct Air Capture of CO2 Using Redox-Active Textiles
• University of Michigan - Systematic Evaluation of Claims Of Excess Heat Generation Form Deuteration Of Palladium-Nickel Nanocomposites
• University of Michigan - Ionizing Radiation Detection for Exploratory Experiments In Low-Energy Nuclear Reactions
• University of Michigan - Development of an Extremely Durable Concrete (EDC) - A Novel Approach Coupling Chemistry and Autogenous Crack Width Control
• University of Nebraska, Lincoln (UNL) - Extrapolation Domains for Aggregating Environmental Outcomes from Local to Regional Levels
• University of Nebraska, Lincoln (UNL) - Novel Commercial Farm-field Network to Quantify Emissions and Carbon Storage from Agricultural Bioenergy Feedstock Production
• University of North Dakota Energy & Environmental Research Center (UND-EERC) - Hydrolytic Softening of Ocean Water for Carbon Dioxide Removal
• University of Notre Dame - GaN Core-shell Nanofin Vertical Transistor (CoNVerT): A New Direction for Power Electronics
• University of Rochester Laboratory for Laser Energetics - LLE Diagnostic Resource Team for the Advancement of Innovative Fusion Concepts
• University of Tennessee, Knoxville (UT) - Ultra-Light Tightly-Integrated Modular Aviation-Transportation Enabling Solid-State Circuit Breaker (ULTIMATE-SSCB)
• University of Texas at Austin (UT Austin) - Nanotechnology-Enabled Transformer Life Extension
• University of Utah - Self-Sustaining Cementitious Systems in Roman Reactive Glass Concretes
• University of Washington (UW) - Parametric Open Data for Life Cycle Assessment
• University of Wisconsin-Madison (UW-Madison) - Multi-Physics Topology Optimization and Additive Manufacturing for High-Temperature Heat Exchangers
• Verdox - Electro-swing Adsorption for High Efficiency Direct Air Capture
• Verne - Decoupling High-Density Hydrogen from the Liquid Hydrogen Infrastructure: Catalyst-Filled Heat Exchangers for Modular Cryo-Compressors
• Virginia Polytechnic Institute and State University (Virginia Tech) - Physical, Chemical, and Mineralogical Characterizations of MSWI Ash Product and Recommendations for Downstream Processing
• Virginia Polytechnic Institute and State University (Virginia Tech) - High Power Density Cost-Effective MV DC Aircraft Cable
• Washington State University (WSU) - Biopolymer Modified Cementitious Systems with Radically Superior Strength and Durability
• Western Research Institute - Polymer/Oil Co-processing to Yield Liquid Products (MEME-CCS)
• WH-Power - Low Cost All Temperature Zinc-pulp Battery for Stationary Storage
• XFlow Energy - Low-Cost Wind Energy Through Dense VAWT Arrays: Fatigue Loads and Power Performance Risk Mitigation
• Zephyr Innovations - Air Conditioning via Liquid Desiccant Dehumidification
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